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Latest Research



Although researchers know several risk factors for prostate cancer, they still are not sure why one man develops the disease and another doesn't.

Lifestyle - Some aspects of a man's lifestyle may affect his chances of developing prostate cancer. For example, some evidence suggests a link between diet and this disease. These studies show that prostate cancer is more common in populations that consume a high-fat diet (particularly animal fat), and in populations that have diets lacking certain nutrients. Although it is not known whether a diet low in fat will prevent prostate cancer, a low-fat diet may have many other health benefits.

Testosterone - Some research suggests that high levels of testosterone may increase a man's risk of prostate cancer. The difference between racial groups in prostate cancer risk could be related to high testosterone levels, but it also could result from diet or other lifestyle factors.

Genetics - Researchers also are looking for changes in genes that may increase the risk for developing prostate cancer. They are studying the genes of men who were diagnosed with prostate cancer at a relatively young age (less than 55 years old) and the genes of families who have several members with the disease.

Men with a family history of prostate cancer who are concerned about an inherited risk for this disease should talk with their doctor. The doctor may suggest seeing a health professional trained in genetics.

Diet - Several studies are under way to explore how prostate cancer might be prevented. These include the use of dietary supplements, such as vitamin E and selenium. In addition, recent studies suggest that a diet that regularly includes tomato-based foods may help protect men from prostate cancer.

Medication - The drug finasteride is being studied in the Prostate Cancer Prevention Trial, which involves thousands of men across the country who are participating for 7 years, until 2004.

Recurrence - Scientists are also looking at ways to prevent recurrence among men who have been treated for prostate cancer. These approaches involve the use of drugs such as finasteride, flutamide, and LH-RH agonists. Studies have shown that hormonal therapy after radiation therapy or after radical prostatectomy can benefit certain men whose cancer has spread to nearby tissues.

Researchers also are investigating whether diets that are low in fat and high in soy, fruits, vegetables, and other food products might prevent a recurrence.


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